Portrait Pro doesn't do anything that you can't do without it, but it expedites a lot of the typical adjustments you'll make to most people photos. It does a great job on skin, provided you fiddle with the settings appropriately. I can see using this for the first pass at least, and, like many Photoshop actions or Lightroom presets, experimentation in Portrait Pro might spark an idea or might highlight an aspect of the image that could benefit from more attention.
I've found some odd color artifacts when making many of the facial modeling and hair coloring adjustments, though these become noticeable only when trying to make fairly drastic changes. The uneven hair adjustment artifacts are evident in the hair below; I could have corrected this easily in the app or in Photoshop, and I probably will go back and make some additional changes later. Even with the most significant artifacts, I found that the "modeled" face offered some interesting potential when saved as a separate image and overlaid manually in Photoshop.
From my brief time using the app, it seems like images shot straight on will work best. I struggled with facial geometry in a shot where the model's head was tipped toward the camera, for example. I don't see Portrait Pro replacing Photoshop for regular image adjustments, but I can see using it all of the time for skin, eyes and teeth.
Here's an image that I thought might particularly benefit from Portrait Pro. I've included the "original," which I made black and white in part to avoid some of the color issues in the capture. I don't like the amount of contrast I used initially, so I've toned that down when re-editing.